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2'-Oxo-PCE (also known as as Eticyclidone, and O-PCE) is a lesser-known novel dissociative substance of the arylcyclohexylamine class that produces dissociative, anesthetic, stimulating and hallucinogenic effects when administered. It is structurally related to arylcyclohexylamines like MXE, 3-MeO-PCE, and deschloroketamine and is speculated to produce its effects through its activity as an NMDA receptor antagonist.

AN ANONYMOUS RESEARCH REPORT ABOUT O-PCE:
... I loved this disso. I regret not getting more of it, as it is somewhat difficult to obtain in my country. It felt very fun, less emotionally numbing than the 3-HO family or memantine - almost similar to ketamine in terms of inebriation/psychedelia, but stimulating rather than sedating ...

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O-PCE stock last updated at: July 2025